UFC 321: Main event, start times, and full card details for Tom Aspinall vs. Ciryl Gane

Tom Aspinall will defend his heavyweight title against Ciryl Gane at UFC 321 on October 25, 2025, in Abu Dhabi. Aspinall, coming off a win over Curtis Blaydes, faces former title challenger Gane, who seeks to re-enter the title picture. The co-main event features Mackenzie Dern against Virna Jandiroba for the vacant strawweight title.