Los Angeles Lakers vs Golden State Warriors (October 21, 2025) prediction, odds, best NBA prop bets, moneyline, spread, and more

The Los Angeles Lakers face the Golden State Warriors on October 21, 2025, for NBA Opening Night. The Warriors are slight favorites at -2.5, with a game total set at 225.5. Despite LeBron James’s absence, Luka Doncic debuts for the Lakers, facing a strong Warriors squad led by Stephen Curry and Jimmy Butler.