New York Knicks vs. Cleveland Cavaliers (10-22-2025) game preview: When and where to watch, expected lineup, prediction, and more

The 2025-26 NBA season kicks off with a highly anticipated matchup between the New York Knicks and the Cleveland Cavaliers on October 22, 2025. Despite both teams facing significant injury concerns, the Knicks will host the Cavaliers at Madison Square Garden, aiming to leverage their home-court advantage for a narrow victory.